Built in 1928, the La Salle Hotel is a 7-story (with basement) 2-part vertical block at the northwest corner of South Main and 27th streets in Bryan, the agricultural and mercantile center of Brazos County, Texas. Designed by Austin architect George Louis Walling, the building features a distinct vertical emphasis and classical detailing, both elements typical of early 20th-century Texas hotels. The ground floor of the rectangular, reinforced concrete frame and masonry building has honed limestone cladding. Cast stone and limestone windowsills detail the masonry upper floors and a recessed cast stone half baluster motif alternates with brick panels at the parapet above a cast stone entablature. Located in the southern part of Bryan’s central business district, the hotel and the surrounding buildings speak to the growth of this commercial area in the early 20th century.